肝硬变患者红细胞血小板参数与直方图分析

An analysis of parameters of red blood cells, platelets and histogram in patients with liver cirrhosis

目的探讨肝硬变患者ＲＢＣ、Ｐｔ参数及其直方图变化规律．方法用Ｆ８００血液分析仪测定３０例肝硬变性贫血患者ＭＣＶ，ＲＤＷ和ＲＢＣ直方图；４２例肝硬变患者Ｐｔ，ＭＰＶ，ＰＤＷ及Ｐｔ直方图，并与５０例正常对照进行比较．结果肝硬变性贫血３０例，类型依次为正细胞不均一性＞大细胞不均一性＞小细胞不均一性＞大细胞均一性＞正细胞均一性．红细胞直方图中５４４％起点小于正常，２３３％大于正常或在正常范围内．８５７％肝硬变患者Ｐｔ＜６０×１０９／Ｌ时并发上消化道大量出血，ＭＰＶ和ＰＤＷ明显增加，Ｐｔ直方图降波呈锯齿状向右延伸．结论根据ＭＣＶ，ＲＤＷ，Ｐｔ，ＭＰＶ，ＰＤＷ及其直方图可确定肝硬变贫血类型，确定治疗方案，判断疗效．

IM To explore the variations of the parameters of RBC, Pt and changes of histogram (HRD) in patients with liver cirrhosis.METHODS The MCV, RDW, RBC and associated HRD of 30 patints with liver cirrhotic anemia and the Pt, MPV, PDW and associated HRD in 42 liver cirrhotic patients were determined with F800 (autoanalytic model). The results were compared with that of 50 normal controls.RESULTS The liver cirrhotic anemia in 30 cases were classified as: nonhomogeneous normal cell type, nonhomogeneous large cell type, nonhemogeneous small cell type, homogeneous large cell type and homogeneous normal cell type. The HRD of RBC showed that 544% of the starting points were lower than the normal, 233% higher than normal or within the normal range. When the Pt count was lower than 60×109/L, 857% of the cirrhotic patients were complicated with profuse bleeding of the upper GI tract, and MPV and PDW markedly increased. HRD of Pt descending flexion appeared serrated extending toward right.CONCLUSION Based on MCV, RDW, Pt, MPV, PDW and relevant HRD detection, the type of cirrhotic anemia and treatment regimen can be determined and prognosis predicted.