后循环缺血性脑卒中的经颅多普勒脑血流速度测定

STUDY OF TRANSCRANIAL DOPPLER OF ISCHEMIC STROKE OF POSTERIOR CIRCLE

目的：经颅多普勒（ＴＣＤ）测定脑干、小脑梗塞与椎基底动脉供血不足患者的脑血流速度的改变，与磁共振成像（ＭＲＩ）进行对比。方法：对６６例临床诊断为后循环缺血性脑卒中患者进行ＭＲＩ和ＴＣＤ检查。将ＭＲＩ显示脑干、小脑有梗塞灶的３６例定为梗塞组；ＭＲＩ未见异常的３０例为椎基底动脉供血不足组（ＶＢＩ）；正常对照组３０例。结果：梗塞组３６例以脑桥梗塞最多见，ＴＣＤ示梗塞组、ＶＢＩ组的血流速度异常率分别为９１６％和６３３％，２组血流速度值与对照组比较均存在显著性差异（Ｐ＜００１）。结论：ＴＣＤ对脑血流动力学的研究有重要应用价值，特别是对于脑ＣＴ、ＭＲＩ等影像学结构改变以前的临床下患者，预防脑梗塞的发生有重要意义。

Objective:To compare the findings of transcranial Doppler(TCD) and magnetic resonance imaging(MRI)of ischemic stroke of posterior circleMethods:TCD and MRI scan in sixtysix patients with clinical diagnosed ischemic stroke of the posterior circle and 30 agematched control subjects were performedResults:MRI scan showed the difference between 36 patients with cerebeller or brain stem infarct lesion(classfied as the infarct group) and another 30 patients who had no abnormal been found(classfied as the vertebralbasilar arteries insufficiency group,VBI)By TCD study,the rate of abnormal cerebral blood velocity was diagnosed in 916% of the infarct group and 663% in VBI groupBetween infarct group or VBI and control group,the difference of abnormal frequency of mean blood velocity or peak blood velocity were significant(P<001)Conclusion:TCD technique could provide reliable information for early diagnosis of ischemic strokeAs a noninvasive technique to evaluate the cerebral circular condition,TCD is an advantageous technique for early diagnosis,treatment and prevention for ischemic stroke