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情感障碍患者血浆孤啡肽含量的初步研究

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摘要 探讨血浆孤啡肽(OFQ)含量与情感障碍之间的相关性。对象共71例,均为山东省精神卫生中心2007年8月至2008年3月的门诊或住院患者,分别符合美国精神障碍分类与诊断标准第4版(DSM—IV)的重性抑郁障碍、双相Ⅱ型障碍抑郁发作和双相I型障碍躁狂发作的诊断标准。其中单相抑郁组24例(男11例,女13例),双相抑郁组21例(男9例,女12例),双相躁狂组26例(男12例,女14例);单相抑郁组、双相抑郁组汉密尔顿抑郁量表(24项,HAMD)总分≥20分,双相躁狂组Bech—Rafaelsen躁狂量表(BRMS)总分≥6分。排除伴有其他精神障碍及物质滥用、依赖者。对照组31名(于2008年1月筛选自山东省精神卫生中心健康职工及家属,男15名,女16名)。
出处 《中华精神科杂志》 CAS CSCD 北大核心 2009年第2期80-80,共1页 Chinese Journal of Psychiatry
基金 基金项目:山东省卫生厅科研基金资助项目(2005HW115)
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参考文献2

  • 1Gavioli EC, Marzola G, Guerrini R, et al. Blockade of noeieeptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test. Eur J Neurosci, 2003, 17 : 1987-1990.
  • 2郑洪波,王斌,张璐璐,泰峰,胡文生,黎娟花.抑郁症患者与健康人血浆孤啡肽含量的初步研究[J].国际医药卫生导报,2007,13(1):4-6. 被引量:9

二级参考文献13

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