高血压靶器官的损害与转化生长因子β1的mRNA关系

Relationship between Target Organ injury of Hypertension and mRNA of Transforming Growth Factor-β1

高血压是一种以体循环动脉收缩压和（或）舒张压升高为特征的临床综合征，它是临床最常见、最重要的心血管疾病之一。转化生长因子β1是目前高血压研究的热点之一，转化生长因子β1与高血压靶器官损害密切相关，其表达水平越高，高血压靶器官损害越重，本文对转化生长因子β1的表达与高血压靶器官损害的关系进行综述。

Hypertension is characterized by the elevated systolic blood pressure and （or） diastolic blood pressure. It is one of the most common and important cardiovascular diseases. Transforming growth factor-β1 is one of research hotspots on hypertension. The expression of TGF-β1 mRNA was closely associated with the target organ damage in hypertension, the higher the expression level, the more severe the target organ injury. This article reviews the relationship between the expression of TGF-β1 mRNA and target organ injury of hypertention.