摘要
目的:探讨早产儿脑室周围白质软化(PVL)发生的高危因素。方法:对2005年1月1日～2007年7月1日入住我院新生儿一科确诊为PVL的早产儿42例(PVL组)和无PVL的早产儿40例(对照组)进行回顾性分析。结果:PVL组与对照组危险因素的单因素分析表明:两组新生儿胎膜早破、窒息、感染、酸中毒、入院1 h动脉氧分压、入院3天内动脉二氧化碳分压、机械通气时间有显著性差异。多因素logistic回归分析表明胎膜早破、窒息、感染、低氧血症和低碳酸血症是PVL的主要危险因素。结论:胎膜早破、窒息、感染、酸中毒、机械通气时间、低氧血症和低碳酸血症是早产儿PVL的高危因素。
Objective： The explore the high risk factors for periventricular leukomalacia （PVL） in preterm infants. Methods： A retrospective analysis was carried out on 42 preterm infants with PVL and 40 preterm infants without PVL from January 1, 2005 to July 1, 2007. Results： There was significant difference in premature rupture of membranes （PROM）, asphyxia, infection, acidosis, PaO2 （with- in the first 24 hours of hospitalization）, PaCO2 （within the first 3 days of hospitalization） and mechanical ventilation between PVL group and control group. The main risk factors for PVL were PROM, asphyxia, infection, hypoxemia and hypocapnia indicated by the logistic regression analysis. Conclusion： PROM, asphyxia, infection, hypoxemia, hypocapnia are high risk factors for preterm infants with PVL.
出处
《中国妇幼保健》
CAS
北大核心
2009年第13期1807-1808,共2页
Maternal and Child Health Care of China
关键词
早产儿
脑室周围白质软化
高危因素
Preterm infants
Periventricular leukomalacia
High risk factors
