摘要
目的：探讨肺癌放疗^18F-FDG PET-CT模拟定位靶区勾画。方法：16例肺癌病人采用GEDiscovery ST16 PET-CT显像和模拟定位,扫描数据DICAM刻盘输入PHILIPS Pinnacle 7.4三维治疗计划系统,放疗科医师对PET影像、CT影像和PET-CT融合影像进行帧对帧对比分析,确认和勾画GTV。结果：12例与PET-CT检查前临床分期一致,4例临床分期提高。13例纵隔淋巴结直径≥1.0cm（1.0-4.2cm）显示高放射性摄取,其中4例同时有直径〈1.0cm的淋巴结也显示为高放射性摄取;3例纵隔淋巴结〈1.0cm无放射性摄取。伴有肺不张的6例中,5例将肿瘤组织与远端肺不张组织区分开来,1例合并阻塞性肺炎与肿瘤组织未能区分。3例化疗后病例显示原发灶和纵隔淋巴结残存或消失。9例PET-CT图像融合精确,7例有不同程度位移。结论：肺癌PET-CT模拟定位,功能影像与解剖影像相结合,使得靶区确认和勾画容易便捷。
Objective：To discuss the GTV delineation of ^18F- FDG PET- CT scan simulation in lung cancer. Methods： Imaging and simulating 16 lung cancer patients by PET -CT scan statistics, burn disks and input the statistics into PHILIPS Pinnacle 7.4 treatment planning system, then contrasting PET- CT fused images, PET images and CT images, radiotherapist identifies and delineates GTV. Results：In the 16 cases, the clinical stage had no change in 12 cases,4 cases were upstaged. PET image showed clear uptake in mediastinal lymph nodes whose diameter≥ 1.0cm（ 1.0 - 4.2cm） in 13 cases,one with 4 cases of which have diameter 〈 1.0cm also showed clear uptake. In 3 cases, mediastinal lymph node whose diameter 〈 1.0cm showed no uptake in PET - CT image. In the 6 cases with pulmonary atelectasis,5 eases clearly divided tumor tissue from atelectatic tissue of lung, 1 case could not divide obstructive pneumonia from tumor. 3 cases showed tumor and mediastinal lymph node＇ s remain or disappear ance after chemotherapy. There were 9 cases of PET - CT image exact fusion,7 cases of displacement. Conclusion： Simulating lung cancer patients by PET -CT imaging,PET- CT functional imaging in combination with anatomical imaging made the GTV identification and delineation easily.
出处
《内蒙古医学院学报》
2009年第2期92-95,共4页
Acta Academiae Medicinae Neimongol
基金
国家自然科学基金项目(30860266)
