急性胰腺炎病因回顾分析

Retrospective analysis on etiology of 265 cases with acute pancreatitis

目的探讨急性胰腺炎患者的发病原因,为急性胰腺炎(AP)的诊治及预防提供依据。方法对我科265例急性胰腺炎患者发病因素进行回顾性分析。结果265例发病患者中,重症急性胰腺炎(SAP)30例,轻症急性胰腺炎(MAP)235例。胆源性77例(29.05%);酒精性25例(9.43%)、暴饮暴食引起30例(11.32%)、ERCP术后胰腺炎10例(3.77%)、高脂血症性9例(3.40%)、特发性AP53例(20%),其中与1种因素有关者108例(40.75%),与2种及以上因素有关者53例(20%)。结论胆道疾病仍是AP主要的病因。AP患者发病因素多而复杂,轻症和重症急性胰腺炎发病因素存在差异。部分患者发病原因仍不明,对于这部分患者应该尽可能寻找病因,以便采取相应防治措施,提高其治愈率,降低复发率。

Objective To study the etiology of acute pancreatitis （ AP）, and to provide references for the clinical diagnosis, relevant prevention and treatment of AP. Methods Retrospective analysis of the etiology of AP was conducted in 265 patients. Results For the 265 acute pancreatitis, 30 patients were severe acute pancreatitis, 235 patients were mild acute pancreatitis. Seventy-seven patients （29.05%） had biliogenic pancreatitis, 25 patients （9.43%） had alco- holic pancreatitis, 53 patients （20%） had idiopathic pancreatitis, 30 patients （11.32%） had binge overeating, 10 pa- tients （3.77%） had postendoscopic retrograde cholangiopancreatography. The percentage of patients with only one fac- tor was about 40.75% , and more than one factor was 20%. Conclusion The results of the present investigation show that biliary tract disease is the main etiology of AP. The etiology of acute pancreatitis are complicated. There is signifi- cant difference among the pathogenic factors of mild and severe acute pancreatitis. For some patients, no specific etiology could be identified. Identification of the possible etiology and taking preventive strategies may improve the effect 6f disease management.