共同性外斜视内直肌病理与手术效果的关系(英文)

Relationship between pathology of concomitant exotropia medial rectus and surgical results

目的:评价内直肌肌细胞数与共同性外斜视手术效果的关系。方法:收集18例共同性外斜视内直肌和14例正常内直肌,行HE染色观察,用斜视积分法评价手术效果。结果:间歇性外斜视组手术前后的斜视积分差显著高于恒定性外斜视(P<0.01);光镜下斜视组内直肌横断面肌纤维排列疏松,间质成分多;斜视组内直肌肌细胞数极显著低于正常内直肌(P<0.01),与病程和手术前后的斜视积分差显著相关(P<0.05)。结论:内直肌肌细胞减少是导致共同性外斜视的直接原因,是斜视手术效果下降的重要因素。

AIM： To evaluate the relationship between the medial rectus cells counts in concomitant exotropia and surgical results. METHODS： A total of 32 pieces of medial rectus muscle were collected for HE staining in this study, of which 18 pieces were from patients with concomitant exotropia and 14 pieces were from healthy individuals. A method of strabismus score was used to assess the operative effect. RESULTS： The difference of strabismus score before and after the operation in the intermittent exotropia group was significantly higher than that in constant exotropic group （P〈 0.01）. Under light microscope, the loosen muscle fibers and the increased stromal components in the cross sectional area of medial rectus were observed in strabismic group. The muscle cells counts was obviously lower in strabismic group than in control group （ P 〈 0.01 ）, which was related to the difference of strabismus score before and after the operation （P〈 0.05）. CONCLUSION. The decreased medial rectus cells counts induce concomitant exotropia directly. It is the crucial causes of the bad surgical results.