福建地区真菌性角膜炎的流行病学研究

Epidemiology of fungal keratitis in Fujian Province

目的:研究福建地区真菌性角膜炎的流行病学特征。方法:回顾性分析2006-07/2008-07住院确诊的真菌性角膜炎患者176例176眼,分析其发病高峰、人群特征、发病诱因、病原学特征。结果:每年10～12月份发病率最高,农村居民106例(60.2%),男女患病率比为1.5∶1,41～60岁为发病集中年龄,仅70例(39.8%)有明确外伤史,菌属鉴定结果:前两位病原菌为镰刀菌属(60.4%)和曲霉菌属(25.4%)。结论:福建地区真菌性角膜炎在10～12月份为高发季节,多发于中老年的农村居民,多数无明显诱因发病,致病菌属以镰刀菌属和曲霉菌属为主。

AIM ： To study the epidemiology of fungal keratitis （FK） in Fujian Province. METHODS= A total of 176 cases （176 eyes） of FK from July 2006 to July 2008 were retrospectively reviewed for the peak period, demographic characteristics, risk factors and etiology characteristic. RESULTS, The peak of FK occurred in every October to December. One hundred and six patients （60.2%） were rural resident. The ratio between the male and female was 1. 5 ： 1. Most patients were 41-60 years old. The history of trauma was clear in 70 patients （39. 8%）. Fusarium species were isolated frequently （60. 4%）, followed by aspergillus （25.4%）. CONCLUSION： In Fujian Province, the peak of FK occurred in October to December. Most patients were the middle-aged in rural resident. There was no significant inducing factor in most patients. The fusarium and aspergillus species were the main pathogens of FK.