以双核铜配合物为中性载体离子电极的研究

Studies on Selective Salicylate Electrode Based on the Schiff Base Complexse of Binuclear Cu(II) as Neutral Carrier

通过对以2,6-二甲酰基4-甲基苯酚缩谷氨酸合二铜(II)配合物Cu(II)2-DFMPG为中性载体的水杨酸根离子选择性电极的研究,发现该电极对水杨酸根(Sal-)具有优良的电位响应性能和选择性,并呈现出反Hofmeister选择性行为。其选择性次序为Sal->SCN>ClO4->I->NO2->NO3->Br->Cl->SO32-。在pH 5.0的磷酸盐缓冲体系中,电极电位呈现近能斯特响应,线性响应范围为4.2×10-5-1.0×10-1 mol/L,斜率为-53.2 mV/dec(25°C),检测下限为2.0×10-5 mol/L。将该电极用于阿司匹林含量测定,与经典分析法相比,结果令人满意。

A novel solvent polymeric membrane electrode based on complexes of binuclear Cu（Ⅱ） is described, which displays a preferential potentiometric response to salicylate and an anti-Hofmeister selectivity sequence in following order： Sal^-〉SCN〉ClO4^-〉I^-〉NO2^-〉NO3^-〉Br^-〉Cl^-〉SO3^2-. The electrode containing 2,6-Bis（hydroxymethymethyl）-4-methylphenol Glutamic acid copperⅡ） E Cu（Ⅱ）2-DFMPG ] has a near Nernstian potentiometric response from 4.2× 10^-5 - 1.0× 10^-1 mol/L with a detection limit 2.0×10^-5 mol/L and a slope of-53.2 mV/dec in pH 5.0 of phosphorate buffer solution at 25℃. The response mechanism is discussed in view of the UV spectroscopy technique. The electrode can be applied to medicine analysis.