汕尾地区妊娠妇女TORCH感染调查分析

Investigation of TORCH Infection in Pregnant Women in Shanwei

目的了解汕尾地区妊娠妇女TORCH感染状况,为预防TORCH感染、降低新生儿出生缺陷发生率提供参考资料。方法采用酶联免疫吸附试验(ELISA)对476例妊娠妇女进行TORCH-IgM及IgG抗体检测。结果TORCH的10项检测结果包括Tox、RV、CMV、HSV-Ⅰ和HSV-Ⅱ的IgM阳性率分别为3.36%、0.84%、2.73%、1.26%和1.68%,Tox、RV、CMV、HSV-Ⅰ和HSV-Ⅱ的IgG阳性率分别为11.10%、86.10%、81.90%、38.40%和15.30%。结论汕尾地区妊娠妇女弓形虫感染率最高,其次是巨细胞病毒。为减少因TORCH感染而导致新生儿出生缺陷,建议妊娠妇女尽可能进行TORCH筛查;孕期TORCH感染者应采取一定的干预治疗措施,必要时终止妊娠,促进优生优育,提高人口素质。

OBJECTIVE To investigate the condition of TORCH infection in pregnant women in Shanwei and provide guidance to reduce birth defect rates by preventing TORCH infection. METHODS Serum samples from 476 pregnant were tested for TORCH-IgM and TORCH-IgG by the enzyme linked immunosorbent assay（ELISA）. RESULTS The IgM positive rates of Tox, RV, CMV, HSV- I and HSV- Ⅱ were respectively 3.36%, 0.84%, 2.73%, 1.26% and 1.68%. The IgG positive rates of Tox, RV, CMV, HSV- I and HSV-Ⅱ were respectively 11.0%, 86.10%, 81.90%, 38.40% and 15.30%. CONCLUSION In this investigation, the infection rates of Tox was the highest in pregnant women in Shanwei, and CMV＇s was the second. Detection for the TORCH was very important to reduce birth defect causing by its infection.To promote eugenic and predisposition level of people, it is needed to get some treatment or stop pregnancy if infected by TORCH in pregnant period.