肿瘤干细胞是中医药防治恶性肿瘤复发转移的可能靶点

Tumor Stem Cells May Be the Final Target of Traditional Chinese Medicine in Preventing Cancer Recurrence and Metastasis

肿瘤的复发转移是导致恶性肿瘤治疗失败的主要原因,寻求防治恶性肿瘤复发及转移的靶点是目前肿瘤研究的重点。研究表明肿瘤干细胞在肿瘤的复发转移中扮演着极其重要的角色,目前尚没有靶向调控肿瘤干细胞功能的成熟的方法。中医药在防治恶性肿瘤复发转移中有较好的疗效,为了更好地发挥这种疗效,并深入探讨其作用机制,应对中医药调控肿瘤干细胞功能进行相关研究,找出中医药作用的最终作用靶点。

The recurrence and metastasis of tumor are the main reasons for the failure in malignant tumor treatments, searching for the best target to prevent the tumor recurrence and metastasis is the focus of tumor research. Research showed that tumor stem cells are the vital factor of malignant tumor recurrence and metastasis, there is no method of target regulating the function of tumor stem cells now. Traditional Chinese Medicine have played a good role in preventing tumor recurrence and metastasis according to the previous studies, so we can suppose that tumor stem cells may be the final target of TCM in preventing tumor recurrence and metastasis. To expand the effect and study the mechanism of action we should introduce the tumor stem cells into the study of TCM in treating malignant tumor.