摘要
介绍了表观遗传学的机制,分析了其改变的特征,并阐述了表观遗传学的研究进展。
出处
《安徽农业科学》
CAS
北大核心
2009年第14期6358-6360,共3页
Journal of Anhui Agricultural Sciences
参考文献19
-
1WOLFFE A P,MATZKE M A. Epigenetics:regulation through repression [J]. Science,1999,286(5439) :481-486.
-
2李著华,王树人.基因的表达调控与Epigenetics[J].四川生理科学杂志,2006,28(1):29-33. 被引量:8
-
3JAENISCH R, BIRD A. Epigenetic regulation of gene ex expression:how the genome integrates intrinsic and environmental signals [ J ]. Not Rev Genet ,2003,33:245 - 254.
-
4MATIAS K P. Study of epigenetic changes leads to treatment advances in adult leukemias [ J ]. Oncolog,2003 ,48 :1 -4.
-
5EHRLINCH M,GAMAR SOSA M A,HUANG L H,et al. Amount and distribution of 5-methyicytosine in human DNA from different types of tissues or cells [ J ]. Nueleic Acids Res, 1982,10:2709 - 2721.
-
6CHEN D,MA H. Regulation of transcription by a protein methyltransferase [J]. Science,199,284:2174 -2177.
-
7NOMA K,ALLIS C D, GBEWAL S I. Transitions in distinct H3 methylation patterns at the heterochromation domain boundaries [ J ]. Science, 2001,293:1150 - 1155.
-
8HANSEN J C,TSE C, WOLFFE A P. Structure and function of the corn histone N-termini: more than meets the eye [ J ]. Biochemistry, 1998,37: 17637 - 17641.
-
9TURNER B M. Histome acetylation and an epigenetic code[J]. Bioassays, 200,22:17636 - 17641.
-
10Y AMAMNOTO Y, VEMA U N,PRAJAPATI S,et al. Histone H3 phosphory lation by IKK-critical for cytokine induced gene expression [ J ]. Nature ,2003,423:655 - 659.
二级参考文献66
-
1Li Hua Liu1,Wen Hua Xiao2,Wei Wen Liu3 1Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China (now working in Department of Gastroenterology, General Hospital of PLA, Lanzhou 730050, Gansu Province, China)2Department of Oncology3Department of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.Effect of 5-Aza-2'-deoxycytidine on the P16 tumor suppressor gene in hepatocellular carcinoma cell line HepG2[J].World Journal of Gastroenterology,2001,7(1):131-135. 被引量:21
-
2Jun Cui,Dong Hua Yang,Xiang Jun Bi,Zi Rong Fan Department of Gastroenterology, Zhujiang Hospital, The First Military Medical University, Guangzhou 510282, Guangdong Province, China.Methylation status of c-fms oncogene in HCC and its relationship with clinical pathology[J].World Journal of Gastroenterology,2001,7(1):136-139. 被引量:16
-
3Jing Yi~1 Zhi-Wei Wang~1 Hui Cang~1 Yu-Ying Chen~1 Ren Zhao~2 Bao-Ming Yu~2 Xue-Ming Tang~1 1 Department of Cell Biology,2 Department of Surgery,Ruijin Hospital,Shanghai Second Medical University,Shanghai 200025,China.p16 gene methylation in colorectal cancers associated with Duke's staging[J].World Journal of Gastroenterology,2001,7(5):722-725. 被引量:21
-
4[1]Bradbury J.Human epigenome project-up and running.http://biology.plosjournals.org 2003; 1:316 ~ 319
-
5[2]Pennisi E.Behind the scenes of gene expression.Science 2001; 293(106):1064 ~1067
-
6[3]Riddihough G & Pennisi E.The evolution of epigenetics.Science 2001;293:106
-
7[4]Fraga MF,Ballestar E,Paz MF,et al.Epigenetic differences arise during the lifetime of monozygotic twins.PNAS USA 2005; 102:10604 ~ 10609
-
8[5]Zambrano P,Pacheco BS,Cardenas EP,et al.A phase 1 study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes.BMC Cancer 2005; 5:44
-
9[6]Jones PA,Takai D.The role of DNA methylation in mammalian epigenetica.Science 2001; 293:1068 ~ 1070
-
10[7]Reik W,Dean W,Walter J.Epigenetic reprogramming in mammalian development.Science 2001; 293:1089 ~ 1092
共引文献62
-
1汪琛颖.表观遗传调控与肿瘤疾病的防治[J].新乡医学院学报,2004,21(6):500-503. 被引量:1
-
2田臻,李江,张志愿.DNA甲基化与口腔癌[J].国外医学(口腔医学分册),2005,32(5):353-355. 被引量:2
-
3张春燕,邹平.表观遗传学及其研究进展[J].四川生理科学杂志,2006,28(2):72-74. 被引量:6
-
4顾婷婷,张忠明,郑鹏生.DNA甲基化研究方法的回顾与评价[J].中国妇幼健康研究,2006,17(6):555-560. 被引量:25
-
5王正朝,潘晓燕,庞训胜.哺乳动物早期胚胎的剂量补偿作用及其对发育的影响[J].家畜生态学报,2006,27(6):202-205. 被引量:2
-
6杨冬,姜颖,贺福初.KAP-1:转录调控中的一个桥梁分子[J].遗传,2007,29(2):131-136. 被引量:9
-
7郭新红,刘文彬.表观遗传学及其研究进展[J].安徽农业科学,2007,35(1):9-10. 被引量:4
-
8马克学,席兴字,李芬.表观遗传修饰与干细胞分化调控[J].生命的化学,2007,27(2):136-138. 被引量:1
-
9张丽霞,潘世扬,陈丹,谢而付,高丽,束永前,陆祖宏,程璐,杨迪,张寄南.肺癌细胞株APC基因启动子甲基化对其转录的影响[J].癌症,2007,26(6):576-580. 被引量:10
-
10杨红丹,高世勇.DNA甲基化异常与人类肿瘤[J].哈尔滨商业大学学报(自然科学版),2007,23(4):393-399. 被引量:1
同被引文献108
-
1李树权,刘素香.DNA甲基化与肿瘤(综述)[J].中国城乡企业卫生,2006,21(3):37-39. 被引量:4
-
2LAN Fei1 & SHI Yang 2 1 Department of Biology, Constellation Pharmaceuticals, 148 Sidney Street, Cambridge, MA 02139, USA 2 Department of Pathology, Harvard Medical School, 77 Ave Louise Pasteur, Boston MA, 02115, USA.Epigenetic regulation: methylation of histone and non-histone proteins[J].Science China(Life Sciences),2009,52(4):311-322. 被引量:27
-
3汪琛颖.表观遗传调控与肿瘤疾病的防治[J].新乡医学院学报,2004,21(6):500-503. 被引量:1
-
4赵洁,苏琦.组蛋白乙酰化/去乙酰化与白血病的研究进展[J].肿瘤学杂志,2004,10(6):436-439. 被引量:19
-
5董玉玮,侯进慧,朱必才,李培青,庞永红.表观遗传学的相关概念和研究进展[J].生物学杂志,2005,22(1):1-3. 被引量:65
-
6JingDeZHU.The altered DNA methylation pattern and its implications in liver cancer[J].Cell Research,2005,15(4):272-280. 被引量:17
-
7于力.DNA甲基化与肿瘤[J].中华内科杂志,2005,44(6):403-404. 被引量:12
-
8张晨辉,王志敏,王艺,黄薇.DNA甲基化与肿瘤发生发展机制研究进展[J].国外医学(肿瘤学分册),2005,32(9):643-646. 被引量:4
-
9申斯乐,王振伟,单晓辉,王华,李玲,林秀云,龙丽坤,翁克难,刘宝,邹广田.高压导致水稻变异品系发生DNA甲基化模式及基因组结构的改变[J].中国科学(C辑),2005,35(6):490-496. 被引量:12
-
10滕玥,戴冬秋.胃癌表遗传学的研究进展[J].世界华人消化杂志,2005,13(19):2289-2293. 被引量:15
引证文献5
-
1徐硕琪.表观遗传学与肿瘤[J].畜牧与饲料科学,2010,31(2):144-146. 被引量:4
-
2王晖,赵亚刚.幽门螺杆菌感染、RUNX3甲基化与胃癌血管生成及淋巴结转移的研究进展[J].临床军医杂志,2012,40(2):493-496.
-
3饶玉春,杨窑龙,马伯军,潘建伟,曾大力.水稻表观遗传的研究进展[J].浙江师范大学学报(自然科学版),2012,35(3):316-321. 被引量:1
-
4王晖,赵亚刚.幽门螺杆菌感染、Runx3甲基化与胃癌关系的研究进展[J].现代消化及介入诊疗,2013,18(1):56-58. 被引量:2
-
5陶艾艾.简析表观遗传学[J].中学生物学,2019,35(11):6-8. 被引量:1
二级引证文献8
-
1姚静,陆岩,黄国良,何志巍.表观遗传在肿瘤发生、诊断及治疗中的作用[J].广东医学院学报,2013,31(3):321-323.
-
2朴智,农晓琳.CpG岛预测方法的选择及评价[J].北方药学,2014,11(3):129-129. 被引量:2
-
3王艳梅,马文双,白静,赵宝华.表观遗传学与肿瘤[J].衡水学院学报,2014,16(4):45-48. 被引量:1
-
4杜童.整体护理在进展期胃癌介入治疗前后的应用价值分析[J].现代消化及介入诊疗,2015,20(3):235-236. 被引量:3
-
5李兰洋.丙泊酚复合全身麻醉与丙泊酚硬膜外麻醉用于胃癌手术的对照分析[J].现代消化及介入诊疗,2015,20(4):356-357. 被引量:8
-
6王杰,徐友信,刁其玉,张乃锋.非孟德尔遗传模式:表观遗传学及其应用研究进展[J].中国农学通报,2016,32(14):37-43. 被引量:2
-
7饶玉春,徐娜,胡娟,焦然,徐江民,宋周琳,黄玲,路梅,王跃星,胡江.水稻类病变突变体spl-3t的精细定位与候选基因分析[J].中国科学:生命科学,2018,48(10):1101-1114.
-
8陆奇,胡官霞,蒋选荣.从表观遗传学视角审视高中生物学中的一些事实与概念[J].生物学通报,2021,56(12):10-13. 被引量:4
-
1何灵江,邵伟.表观遗传学研究进展[J].生物学教学,2008,33(5):5-7. 被引量:3
-
2文戈,田云,方俊,卢向阳.表观遗传与分子育种[J].江西农业学报,2011,23(6):23-24. 被引量:1
-
3邵新亮,和绍禹,李亚辉.表观遗传学在雌性蜜蜂级型分化研究中的应用[J].蜜蜂杂志,2010,30(9):20-22. 被引量:1
-
4余丽.表观遗传学的研究和发展[J].安徽农业科学,2010,38(2):588-591. 被引量:6
-
5洪林,魏召新,魏文辉,谭平.染色质重塑及其参与植物病害防御应答的研究进展[J].植物保护,2016,42(4):9-17. 被引量:1
-
6朱景德.组学时代的表观遗传学研究的机遇和挑战[J].中国科学基金,2009,23(4):196-202. 被引量:4
-
7肖旭峰,范淑英.抽薹开花抑制因子FLC表观遗传调控研究进展[J].中国蔬菜,2013(11X):1-8. 被引量:4
-
8郭龙芳,薛福东,郭九峰,那日.Plant Tissue Culture: A Recent Progress and Potential Applications[J].Agricultural Science & Technology,2014,15(12):2088-2095. 被引量:5
-
9徐晶,盛慧,蒲国锋.表观遗传学的研究进展[J].蔬菜,2012(5):46-47.
-
10薛涛涛,边金,伍陆,赵秀娟,崔向军,蔡禄.酿酒酵母组蛋白H3K56A突变菌株的构建及其对细胞生长的影响[J].江苏农业科学,2016,44(12):77-81.