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过氧化物酶体增殖物激活受体γ途径抑制肿瘤血管生成的研究进展

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作者 夏启松 修瑞娟 孙仁宇
机构地区 中国医学科学院中国协和医科大学微循环研究所
出处 《肿瘤防治研究》 CAS CSCD 北大核心 2009年第5期443-447,共5页 Cancer Research on Prevention and Treatment
关键词 过氧化物酶体增殖物激活受体Γ 血管生成 肿瘤治疗
分类号 R730.23 [医药卫生—肿瘤]
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参考文献45

  • 1Issemann I, Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators[J]. Nature, 1990, 347(6294) : 645-650.
  • 2Panigrahy D, Huang S, Kieran MW, et al. PPARgamma as a therapeutic target for tumor angiogenesis and metastasis[J]. Cancer Biol Ther, 2005, 4(7), 687-693.
  • 3Fajas L, Auboeuf D, Raspe E, et al, The organization, promoter analysis, and expression of the human PPARgamma gene[J]. J Biol Chem, 1997, 272(30): 18779-18789.
  • 4Lehrke M, Lazar MA. The many faces of PPARgamma[J]. Cell, 2005, 123(6): 993-999.
  • 5Yang Y, Shang W, Zhou L, et al. Emodin with PPARgamma ligand-binding activity promotes adipocyte differentiation and increases glucose uptake in 3T3 LI cells[J]. Biochem Biophys Res Commun, 2007, 353(2); 225-230.
  • 6Tsuzuki T, Kawakami Y. Tumor angiogenesis suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via peroxisome proliferator-activated receptor gamma[J]. Carcinogenesis, 2008, 29(4): 797-806.
  • 7Llpenberg A, Jeannin E, Wahli W, et al. Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. A functional analysis of the malie enzyme gene PPAR response element[J]. J Biol Chem, 1997, 272(32): 20108- 20117.
  • 8Burns KA, Vanden Heuvel JP. Modulation of PPAR activity via phosphorylation[J]. Biochim Biophys Acta, 2007, 1771 (8) : 952-960.
  • 9Pascual G, Fong AL, Ogawa S, et al. A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma [J]. Nature, 2005, 437 (7059) : 759-763.
  • 10Yamashita D, Yamaguchi T, Shimizu M, et al. The transactivating function of peroxisome proliferator-activated receptor gamma is negatively regulated by SUMO conjugation in the amino-terminal domain[J]. Genes Cells, 2004, 9 ( 11 ) : 1017- 1029.

二级参考文献25

  • 1朱理辉,张琍.PPARγ激活剂罗格列酮抑制人胃癌MGC803细胞增殖机制的研究[J].实用癌症杂志,2005,20(6):564-567. 被引量：5
  • 2[1]Berger J,Moller DE.The mechanisms of action of PPARs.Annu Rev Med,2002,53:409-435.
  • 3[2]Collett GP,Betts AM,Johnson MI,et al.Peroxisome proliferatoractivated receptor alpha is an androgen-responsive gene in human prostate and is highly expressed in prostatic adenocarcinoma.Clin Cancer Res,2000,6:3241-3248.
  • 4[3]Boast K,Binley K,Iqball S,et al.Characterization of physiologically regulated vectors for the treatment of ischemic disease.Hum Gene Ther,1999,10:2197-2208.
  • 5[4]Chen F,Law SN,O'Malley BW.Identification of two mPPAR related receptors and evidence for the existence of five subfamily members.Biochem Biophys Res Commun,1993,196:671-677.
  • 6[5]Zhu Y,Alvares K,Huang Q,et al.Cloning of a new member of the peroxisome proliferator activated receptor gene family from mouse liver.J Biol Chem,1993,268:26817-26820.
  • 7[6]Kang HY,Lee JY,Lee JS,et al.Peroxisome proliferator-activated receptors-gamma activator,ciglitazone,inhibits human melanocyte growth through induction of apoptosis.Arch Dermatol Res,2006,297:472-476.
  • 8[7]Huang WC,Chio CC,Chi KH,et al.Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta (12,14) -prostaglandin J (2),ciglitazone,and GW1929.Exp Cell Res,2002,277:192-200.
  • 9[8]Brockman JA,Gupta RA,Dubois RN.Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells.Gastroenterology,1998,115:1049-1055.
  • 10[9]Morrison RF,Farmer SR.Role of PPARgamma in regulating a cascade expression of cyclin-dependent kinase inhibitors,p18 (INK4c)and p21 (Waf1/Cip1),during adipogenesis.J Biol Chem,1999,274:17088-17097.

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肿瘤防治研究
2009年 第5期

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