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氨基末端脑钠肽前体在心功能不全诊治中的临床价值

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摘要 目的探讨氨基末端脑钠肽前体(NT-proBNP)与心功能不全之间的关系。方法78例心功能不全患者根据NY-HA心功能不全分级分为4组,采用电化学发光法检测4组患者NT-proBNP的浓度变化。心功能Ⅲ、Ⅳ级的患者经过3 d和7 d抗心衰治疗症状改善后复查NT-proBNP并与之前比较。结果NT-proBNP浓度与NYHA心功能不全分级密切相关(P<0.05),NT-proBNP浓度随着心功能不全程度的加重而增加。心功能Ⅲ、Ⅳ级患者经过3 d和7 d治疗,心功能改善后NT-proBNP浓度比治疗前显著降低,差异有统计学意义(P<0.05)。结论NT-proBNP作为心功能不全的指标,对心功能不全的严重程度和疗效判定有着重要临床价值。
作者 孙毅 谢文卓
出处 《广西医学》 CAS 2009年第4期541-542,共2页 Guangxi Medical Journal
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