辅助生殖技术周期中子宫内膜变化与妊娠关系

The Relationship between Endometrium Change and Pregnancy in Assisted Reproductive Technology Cycle

在辅助生殖技术(ART)中,子宫内膜是成功妊娠的关键因素之一。内膜受到患者本身体质、激素水平及其他因素的影响而发生变化,子宫内膜的异常变化会导致胚胎的种植率和妊娠率降低。临床上希望通过超声下观察子宫内膜的厚度和形态来衡量内膜的容受情况,以期对成功妊娠作出指导。但是至今关于内膜变化与妊娠的关系还无确切定论。同时年龄、药物等多种因素都会对内膜的厚度及形态产生影响。对以上相关研究结果做综述。

Endometrium is one of the most crucial factors for successful pregnancy in assisted reproductive technology （ART）. It is influenced by individual constitution, hormone levels and other factors. The abnormal changes of endometrium will induce the decrease of embryo implantation rate and pregnancy rate. Clinical doctors wish to provide guidance for successful pregnancy with the evaluation of endometrial receptivity through the observation of endometrial thickness and morphous using uhrasonography. However, up to now, there are no definite conclusions about the relationship between endometrium changes and pregnancy. Meanwhile, age, drug and many other factors will influence endometrial thickness and morphous. This article reviews recent progress of related studies mentioned above.