摘要
通过对狗的脾脏进行a受体阻断情况下的低浓度肾上腺素溶液在体 灌注实验,探讨了脾脏储存与释放血细胞的微循环动力机制.实验结果支持Groom 提出的脾索内肌质纤维在交感神经控制下的血液调节机制,并认为脾索及静脉窦 壁的过滤作用是调节脾内红细胞浓度的主要因素,但并非如 Mackenzie和 J rgen 等人认为的红细胞被动地滞留于脾索中,而是存在交感神经及血液中儿茶酚胺调 控下的主动机制。
The splenic red blood cell reserve and discharge mechanism was studied by perfusing adrenaline solution of low concentration into splenic arteries after a-receptors in the spleen were blocked in anaesthetized dogs. The analysis to the experiments supports the splenic blood regulation mechanism involving active contraction of intra-reticulocytic skeletal filamets under the control of sympathetic nerve proposed by Groom. Red blood cells are not reserved passively by filtration of the red pulp as Mackenzie and Jorgen suggested, but by active dilation of reticulocytes or endotheliocytes of venous sinuses controlled sympathetic nerve and catechnolamine in blood.
出处
《中国血液流变学杂志》
CAS
1998年第1期8-12,共5页
Chinese Journal of Hemorheology
关键词
脾脏
红细胞
肾上腺素能受体
血球比积
Spleen Red blood cell (RBC) Adrenergic receptor Haematocrit