颈动脉灌注治疗脑血管病的临床研究

A Clinical Study on Therapy for Cerebrovascular Accident with Perfusion by way of Carotid Artery

目的：评价颈动脉灌注法治疗脑血管病的治疗效果。方法：对30例脑血管意外（颈内动脉系）急性期、恢复期、后遗症期患者，用常规加颈动脉穿刺分别灌注由尿激酶、svate—3、普鲁卡因等组合成的瘫复Ⅰ、Ⅱ、Ⅲ、Ⅳ号方法治疗，共10次，与常规治疗组30例作对照比较。结果：两组总有效率分别是96．7％和83．3％（P＞0．05），但总显效率（痊愈＋显著进步）为76．7％和16．7％（P＜0．001），差异极显著。提示脑血栓的溶栓在12h内效果最佳，48h内仍有效；瘫复Ⅳ号对脑出血恢复期治疗有显著效果。结论：认为此疗法具疗效好、见效快、安全、简便易行等优点。

OBJECTIVE:to observe the curative effect for cerebrovascular accident with per fusion by way of carotid artery. METHODS: 30 cases of cerebrovascular accident (internal carotid system) of acute and convalescence and sequela phase were treated with together routine treatment and perfused injection Tanfu No. Ⅰ、Ⅱ、Ⅲ、Ⅳ, which is composed of urokinase、svate - 3. procaine,etc,by way of carotid artery, once daily,for a total of 10times,and the orther 30 cases with routine treatment as a contrast group. RESULTS: the results showed that the total rate of clinical effectiveness for the study group was 96. 7% compared to 83. 3% for the contrast group (P>0. 05), but the rate of notable effectiveness (togather cured and marked progress) was 76. 7%compared to 16. 7% between them (P<0. 001). It is felt that best is effect of dissolution thrombus for cerebral thrombosis within 12 hours,and it is still effective within 48hs,and injection Tanfu No. Ⅳ have a notable efficacy for cerebral hemorrhage of non - acute stage. CONCLUSION: We believe that this method possesses a well and quick efficacy, it is safe and easy to operate,therefore,is advanced and usefulness.