尼莫通治疗重型颅脑损伤后昏迷效果的相关分析

Correlation analysis about the effect of nimotop for treatment of comas after severe head injury

目的：探讨尼莫通治疗重型颅脑损伤后昏迷的治疗效果与患者伤后（或术后）时间的相关性。方法：对76名重型颅脑损伤后昏迷在常规治疗基础上加用尼莫通一个疗程。患者治疗前后的GCS分数差作为疗效指标，患者从伤后（或术后）到首次使用尼莫通的时间作为伤后时间指标，对治疗效果与伤后时间两因素进行相关分析。结果：相关系数R=-0.4369且P＜0.01，说明疗效与伤后时间两因素之间存在负相关关系，且相关系数有高度相关性。结论：提示重度颅脑损伤后患者应尽早使用尼莫通。

Objective:To study the correlation between the effect of nimotop and the time after injury(or operation)in severe head injury. Methods: 76 patients with severe head injury were treated by nimotop for a treatment -term. The balance of GCS grade before and after treatment is as the effect,the time from injury(or operation)to first use of nimotop is as the time after injury. Above tow actors were evaluated with correlation analysis. Results: R= - 0. 4369 P＜0.01, It showed negative correlation and marked -sig-nificance. Conclusions:the result prompt that the patients of severe head injury should be treated with ni-motop as early as possible.