角膜碱烧伤早期自由基清除剂治疗的实验研究

An Experimental Study of Alkali Burns of Cornea Treated with The Scavengers of Free Radicals

目的：探讨眼前段碱烧伤后自由基清除剂治疗的疗效。方法：动物分成4组，分别为：对照组、超氧化物歧化酶组（SOD组）、过氧化氨酶（CAT）组及SOD＋CAT联合治疗组进行疗效观察。结果：SOD＋CAT联合治疗组与烧伤组相比角膜溃疡发生率低，P＜0．01，疗效显著。结论：眼前段碱烧伤后眼组织病理生化涉及到自由基的生成，采用自由基清除剂从不同方面治疗碱烧伤有临床实用价值。

Purpose: Evaluate the usage of scavengers of free radicals after alkali burns of cornea.Methods:Rabbits were divided into 4 groups:SOD、CAT、SOD+CAT and Contrasted group. Resalts:SOD+CAT group has an lower level of cornea ulcer as compared with that of contrasted group, (P＜0.01 )．Conclusion: Using of SOD and CAT after alkali burns of cornea has a significant result , for it's the twomain scanvengers of free radicals after alkali burn of cornea.