釉基质蛋白在口腔医学领域中的研究进展

Research progress of emdogain in the field of stomatology

釉基质蛋白为釉基质衍生物与其相应载体的结合物,具有促进牙周组织的再生、生物矿化和骨诱导等生物特性。研究者们已从体外培养、动物和临床试验对其进行研究并初具成果,笔者就釉基质蛋白及其与牙周疾病、颌面部骨缺损和牙种植以及其他口腔疾病的关系作一综述。

Emdogain is the conjugate of enamel matrix derivative and corresponding carrier, which can promote regeneration of periodontal tissues, biomineralization, bone induction and so on. Many researchers reached some resuhs in emdogain from culture in vitro, animal studies and clinic trials. This review summarized emdongain and its role in periodontal disease, maxillofacial defects, dental implantation and so on.