蒙药光明盐四味汤散对大鼠酒精性肝损伤的保护作用

Protection effect of Mongolian Medicine bright salt-4 decoction on alcohol-induced liver injury in rats

目的：蒙药光明盐四味汤散对大鼠酒精性肝损伤的保护作用。方法：采用Wistar雄性大鼠105只，随机分为7组。采用白酒灌胃的方法建立大鼠酒精性肝损伤模型，同时给予蒙药光明盐四味汤散保护。检测血清中ALT、AST，HE染色观察肝脏的病理变化。结果：蒙药光明盐四味汤散降低血清中ALT、AST，明显改善肝组织脂肪样变。结论：蒙药光明盐四味汤散对酒精性肝损伤有明显的保护作用。

Objective：Mongolian Medicine bright salt -4 decoction on rat-alcohol-induced liver injury in. Methods： Using 105 Wistar male rats were divided into seven groups.Liquor gavage method used in the establishment of alcoholinduced liver damage model, at the same time the rats were orally administrated with bright salt -4 decoction respectively dosage. Detection of serum ALT, AST, HE staining of the pathological changes in liver. Results： Mongolian Medicine bright salt -4 decoction lower serum ALT, AST, marked improvement in liver fat-like change. Conclusion： Mongolian Medicine bright salt -4 decoction alcohol-induced liver injury has protective effect.