动态监测心肌酶谱在新生儿感染性疾病中的临床意义

Clinical significance of serum myocardial zymogram in neonatal infectious diseases

目的探讨心肌酶活性水平变化在新生儿感染性疾病中的临床意义。方法选择新生儿感染性肺炎(肺炎组)35例,新生儿败血症(败血症组)29例,检测它们在治疗前后的心肌酶活性水平,进行各项值治疗前后及两组间对比。结果治疗前,两组心肌酶活性水平均高于正常值,败血症组高于肺炎组(P<0.05);治疗后,两组心肌酶活性水平明显下降(P<0.05)。结论心肌酶活性水平对感染损伤反应灵敏,且与感染的严重程度相关。

Objective To investigate the clinical significance of myocardial zymogram activity in neonatal infectious diseases. Methods 64 cases were divided into 2 groups, including group of neonatal infectious pulmonitis （35cases） and group of neonatal septicemia （29 cases）, in which the level of myocardial zymogram has been detected before and after treatment, respectively. The effect was analyzed. Results Before treatment, the myocardial zymogram activity of the cases was beyond the normal value, especially that of the group of neonatal septicemia was higher than that of other group （P〈0.05）. However, after treatment, all the values have obviously decreased （P〈0. 05）. Conclusion The myocardial zymogram is a sensitive marker for infectious injury response. Moreover, the level of this marker is related to the injury severity of infection.