正清风痛宁联合甲氨蝶呤对类风湿性关节炎的治疗价值

The effect of ZhengQinFengTongNing for rheumatoid arthritis therapy combined with methotrexate

目的观察正清风痛宁联合甲氨蝶呤治疗类风湿性关节炎的疗效。方法将80例类风湿性关节炎患者,随机分为治疗组42例和对照组38例。对照组予甲氨蝶呤联合柳氮磺吡啶,以及对症治疗;治疗组以正清风痛宁联合甲氨蝶呤治疗,疗程均为半年。结果坚持治疗半年后,两组病人的关节疼痛、肿胀、压痛,关节活动度、晨僵时间,均有明显的改善与好转,但治疗组总有效率95.2%(40/42),疗效明显优于对照组的82.5%(33/38);(P<0.05),且副作用轻微。结论正清风痛宁联合甲氨蝶呤治疗类风湿性关节炎,效果显著,且安全性与依从性好。

Objective To observe the treatment effect of Zhengqinfengtongning for rheumatoid arthritis therapy combined with methotrexate. Methods 80 patients with rheumatoid arthritis were randomly divided into two groups, 42 cases in treatment group and 38 cases in control group. The control group was treated by methotrexate combined with sulfasalazine according to their symptom and treatment group was treated by Zhengqinfengtongning combined with methotrexate. Results After the treatment for six months, the symptoms including joint pain, swelling, tenderness, range of motion and morning stiffness of the two groups alleviated. The total effective rate of treatment group and control group were 95.2% （40/42） and 82.5% （33/38） （P〈0.05）, respectively. The side effect was less in treatment group compared that in control group. Conclusion There is a significant treatment value of ZhengQinFengTongNing for rheumatoid arthritis therapy combined with methotrexate.