摘要
拉米夫定是一种纯左旋对映体形式的脱氧胞密啶类似物,能够抑制HBV聚合酶,阻断HBV-DNA的合成与复制。联合中药可以发挥中药多层次、多方位、多靶点的打击特点,较大程度上遏制HBV变异,进而提高抗病毒效应及降低耐药性。
Lamivudine is a pure L - enantiomer forms of deoxy - cell Micronesia acridine analogues, can inhibit HBV polymerase, blocking HBV - DNA synthesis and replication. Chinese medicine combined with traditional Chinese medicine can play a multi - level, multi - directional, multi - target anti - features, up to a greater extent to contain HBV variant,which enhance anti -viral effects and reduce drug resistance.
出处
《实用中医内科杂志》
2009年第5期76-77,共2页
Journal of Practical Traditional Chinese Internal Medicine
关键词
拉米夫定
中药
耐药性
lamivudine
chinese medicine
resistance
