摘要
Therapeutic efficiency of advanced stage liver cancer is insufficiency,which has become the hot spot of research.Clinical observation found that prognosis of liver cancer with integrity amicula was better.It is generally accepted that silicon dioxiode(SiO2) can induce pulmonary fibrosis,resulting in the formation of pneumosilicosis.Use of SiO2 as embolism material induces hepatic fibrosis and forms the fibrosis amicula around the liver carcinoma,and then restrains the recurrence and metabasis of liver cancer,which has been turned into one of the aspect of liver carcinoma therapy.The possible mechanisms of inducing hepatic fibrosis by SiO2 are peroxidative damage by free radical,releasing of active cytokines,or inducing cell apoptosis and the activation of HSC etc.
Therapeutic efficiency of advanced stage liver cancer is insufficiency, which has become the hot spot of research. Clinical observation found that prognosis of liver cancer with integrity amicula was better. It is generally accepted that silicon dioxiode （SiO2 ） can induce pulmonary fibrosis, resulting in the formation of pneumosilicosis. Use of SiO2 as embolism material induces hepatic fibrosis and forms the fibrosis amicula around the liver carcinoma, and then restrains the recurrence and metabasis of liver cancer, which has been turned into one of the aspect of liver carcinoma therapy. The possible mechanisms of inducing hepatic fibrosis by SiO2 are peroxidative damage by free radical, releasing of active cytokines, or inducing cell apoptosis and the activation of HSC etc.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2009年第5期1022-1025,共4页
Chinese Journal of Pathophysiology
基金
广东省自然科学基金资助项目(No.C03030303)
