慢性肝性脑病的磁共振成像及其波谱表现

MRI and MRS Findings of Chronic Hepatic Encephalopathy

目的:分析慢性肝性脑病的MRI及其波谱特点,探讨其诊断价值。材料和方法:对8例慢性肝性脑病行MRI及1H-MRS STEAM法检查,观察慢性肝性脑病MRI图像表现及波谱图像主要代谢峰Cho、mI、Glx、NAA、Lip/Lac的变化。结果:4例肝性脑病MRI图像出现苍白球及邻近区域对称性短T1等T2信号影,1例出现基底核团对称性长T1长T2信号影,1例同时出现上述两种改变,2例无明显改变。波谱图像上均表现为Cho、mI降低,Glx升高、NAA、Lip/Lac改变不明显。结论:慢性肝性脑病MRI具有表现特点,波谱能准确、较早反映脑内代谢变化。

Purpose： To study the features of MRI and MRS of chronic hepatic encephalopathy. Materials and Methods： The signal changes observed on MRI images and Cho,mI,Glx,NAA ,Lip/Lac manifestation on MRS in 8 patients with chronic hepatic encephalopathy. Results： Of 8 patients, 4 appeared signal hyperintense on T1WI and isointense on T2WI in bilateral globuses, 1 appeared hypointense on T1WI and hyperintense on T2WI in bilateral basal nuclei, 1 appeared both above,2 appeared normal signal. All 8 patients appeared decreased mI and Cho, increased Glx, normal NAA and Lip/Lac. Conclusion： Chronic hepatic encephalopathy has its features in images of MRI. MRS can refelect metabolism changes more accurately and early.