2005～2008年我院抗菌药物应用分析

Utilization of Antibacterials in Our Hospital During 2005～2008

目的:了解我院抗菌药物用量的变化趋势,为医院药品管理和临床合理用药提供依据。方法:选取2005～2008年我院用药分析系统中抗菌药物的数据资料,用限定日剂量(Defined daily dose,DDD)分析法及消耗金额统计法,分析用药频度(DDDs)和药物费用。结果:从2005～2008年,头孢菌素类无论是品种数量还是销售金额始终排在第1位,且呈现逐年增长的趋势。β-内酰胺类抗菌药物占绝对优势。结论:随着抗菌药物的大量使用,细菌耐药性不断发展,合理使用抗菌药物是我们面临的重要课题。

OBJECTIVE： To investigate the trend in the application of antibacterials in our hospital for references of hospital drug management and clinical rational drug use. METHODS： Data about the antibacterials used in our hospital during 2005 - 2008 were retrieved from the medication analytical system with DDDs and drug cost analyzed using the method of defined daily dose （DDD） and a statistical method of consumption sum, respectively. RESULTS： Cephalosporins topped the list in both variety and consumption sum during the period 2005 - 2008 and which assumed a year - on - year increase tendency. The consumption of β - lactam antibacterial assumed a predominant place. CONCLUSION： The bacterial drug resistance is increasing with the extensive use of antibacterials, so rational use of antibacterials has become an important question for study.