摘要
目的:比较5种药物治疗老年抑郁症的疗效及经济学效果。方法:将符合抑郁症诊断标准的门诊患者共128例,随机分为A组(帕罗西汀)、B组(文拉法新)、C组(西酞普兰)、D组(米氮平)、E组(米安色林),均口服给药,治疗6周,观察疗效,并进行成本-效果分析。结果:A、B、C、D、E方案总有效率依此为为90.62%、93.33%、90.00%、90.32%、87.50%;成本-效果分别为512.82、406.98、491.40、613.20、291.48。结论:B组方案较佳。
OBJECTIVE： To compare the curative effects and pharmacoeconomic efficacies among five drugs in the treatment of senile patients with depression. METHODS： A total of 128 senile patients meeting the diagnostic criteria for depression were randomly divided into one of the following five groups： Group A （Paroxetine）, Group B （Venlafaxine）, Group C （Citaiopram）, Group D （Mirtazapine）, and Group E （Mianserin）. All the drags were taken orally. After treatment for 6 weeks, the clinical efficacy was observed and the cost - effectiveness analysis was performed. RESULTS： The total effective rates of the five groups （A, B, C, D, and E） were 90.62%, 93.33%, 90.00%, 90.32% and 87.50%, respectively; the cost - effectiveness ratios were 512. 82, 406. 98. 491. 40. 613 20 and 291. 48, respectively.CONCLUSION： Group B （Venlafaxine） was the optimal regimen for depression in senile patients in terms of the cost -effectiveness.
出处
《中国医院用药评价与分析》
2009年第4期293-295,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
