摘要
目的:观察泮托拉唑联合奥曲肽在非静脉曲张性上消化道大出血中的治疗效果。方法:将155例非静脉曲张性上消化道大出血患者随机分成2组,单纯泮托拉唑治疗65例(对照组),奥曲肽+泮托拉唑治疗70例(治疗组),持续应用72 h。结果:对照组65例中,41例出血停止,止血率60.00%,治疗组70例中,67例出血停止,止血率96.71%,治疗组止血率明显优于对照组,经χ2检验有极显著性差异(P<0.001)。结论:泮托拉唑+奥曲肽对非静脉曲张性上消化道大出血有较好疗效,可降低急诊手术率和病死率。
OBJECTIVE： To observe the efficacy of Pantoprazole in association with Octreotide for non - variceal upper gastrointestinal bleeding. METHODS： A total of 155 patients with non - varicosity upper gastrointestinal bleeding were randomly assigned to receive Pantoprazole alone （n = 65, control group） or Pantoprazole in association with Octreotide （n = 70, trial group） for 72h. RESULTS： The 2 test showed that there were significant differences between the two groups in haemostatic rate （60.00% （41/65） in the control group versus 96.71% （67/70）） in the trial group （P 〈 0.001）. CONCLUSION： The efficacy of Pantoprazole in association with Octreotide for non - variceal upper gastrointestinal bleeding is remarkable and it is conducive to the reduction of emergency operability and case fatality.
出处
《中国医院用药评价与分析》
2009年第4期300-301,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
非静脉曲张性
消化道出血
奥曲肽
泮托拉唑
Non - variceal
Gastrointestinal bleeding
Octreotide
Pantoprazole
