摘要
目的分析神经梅毒的临床特征及提供早期诊断依据。方法回顾性分析经临床和实验室检查确诊的3例神经梅毒患者的临床资料和有关资料。结果神经梅毒的临床特征包括:①急性、亚急性起病多,少数慢性起病;②临床以间质型,尤其脑卒中最常见;③螺旋体明胶凝集(TPPA)试验及梅毒快速血浆反应素试验(RPR)阳性率极高;④脑脊液检查表现为蛋白含量增加、细胞数增多(以淋巴细胞为主);⑤头颅CT或MRI表现与高血压、糖尿病所致常见的脑梗死不同,病灶多发,可分布在脑的所有部位。结论神经梅毒的临床特征没有特异性,误诊率高,临床表现、实验室及影像学检查是其诊断的重要依据。
Objective To analyse the clinical features of neurosyphilis in order to help early diagnosis. Methods A retrospective analysis in 3 cases of neurosyphilis diagnosed by clinical and laboratoPy examinations was focused on their clinical manifestations. Resealts The clinical features of neurosyphilis: (1)Acute or subacute onset was common, while chronic onset was minority;(2)Interstitial neurosyphilis, especially cerebral infarction was the common sort in the clinical;(3)TPPA test and RPR test were of the highest specificity among the seMogic tests;(4)CSF examination revealed that CSF protein content was increased significantly, and cells count, mainly lymphocytes increased;(5)Cranial CT/MRI findings revealed multiplex, asymmetrical lesions, which were different from those of cerebral infarctions caused by hypertension or diabetes. Conclusion Neurosyphilis has a high misdiagnosis rate, and its diagnosis depends on clinical manifestations, laboratory and imaging examinations.
出处
《安徽医学》
2009年第4期423-425,共3页
Anhui Medical Journal
关键词
神经梅毒
临床表现
诊断
Neurosyphilis
Clinical manifestations
Diagnosis