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小胶质细胞免疫功能的研究进展 被引量：1

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摘要 1 小胶质细胞起源、形态及活化机制 研究认为，小胶质细胞来源于间充质中胚层的巨噬细胞，于胚胎发育期进入脑组织，并在血一脑脊液屏障（Blood--brain barrier，BBB）形成之后留存，其功能类似于巨噬细胞，从形态上可分为分枝状和阿米巴状，形态不同，其功能状态也不同，前者代表静止的小胶质细胞，后者代表激活的小胶质细胞。其形态取决于脑区结构：若小胶质细胞周围有足够空间，其形态就变得松散；反之，变为细长柱状。
作者 赵海霞 杨淑云 赵金霞 康义 叶静
机构地区 武警山西总队医院神经内科 首都医科大学附属宣武医院
出处 《武警医学》 CAS 2009年第5期473-474,共2页 Medical Journal of the Chinese People's Armed Police Force
关键词 中枢神经系统 小胶质细胞 抗原提呈
分类号 R392 [医药卫生—免疫学]
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参考文献17

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共引文献10

同被引文献30

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  • 3罗晓光,周进,葛春林,任艳,闫荣,吴哲,王秋爽,张朝东.损伤神经环境中小胶质细胞促进MSCs神经营养功能的信号传导通路初探[J].中国免疫学杂志,2007,23(8):721-724. 被引量：1
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武警医学
2009年 第5期

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