葛根总黄酮治疗低雌激素咽黏膜病变的临床应用研究

Clinical Research of Pueraria Total Flavonoids in The Treatment of Pharyngeal Mucous Membrane Lesion Induced by Low Estrogen

目的探讨葛根总黄酮治疗低雌激素咽黏膜病变的临床应用。方法选择停经1年及以上的绝经期妇女,病史与临床检查符合干燥、萎缩性咽炎,无妇科及脑部肿瘤,无糖尿病、甲亢、肝肾疾病的患者150例,给予葛根黄酮胶囊,3次/d,每次2粒,用药时间为30d,用药时间内停其他治疗,采用自身前后对照。结果与治疗前比较葛根总黄酮可恢复更年期妇女的雌激素水平。结论葛根总黄酮对低雌激素水平所致的咽黏膜干燥、萎缩,具有良好的治疗作用。

Objective to investigate the clinical application of pueraria total oflavone on pharyngeal mucous membrane lesion induced by low estrogen. Methods We selected 150 menopause women who had been menelipsis for more than 1 year. Their history and clinical examination corresponded dry and atrophic pharyngitis, without gynecology tumor or cerebral tumor, diabetes, hyperthyreosis, liver or kidney disease. We gave them purearia isoflavone, 2 tablets, 3 times/ day. The duration was 30 days. During these days, they stopped other treatment. And we compared them between before and after treatment. Results Purearia total oflavone could recover estrogen level of menopause women, compared with before this treatment. Conclusion Purearia total oflavone has excellent therapeutic effect on dry and atrophy of pharyngeal mucous membrane induced by low estrogen.