心肌组织工程研究进展

Progresses in Myocardial Tissue Engineering

心肌组织工程的目的在于利用体外构建的组织修复、替换及再生受损心肌。我们综述了心肌组织工程中的最新方法及其在体内的初步应用,讨论了心肌组织工程的细胞来源和支架材料,提出了现存障碍。心肌组织工程的替代治疗具有极其诱人的前景,但是它还处于早期阶段,仍然需要对其真正的价值做出合适的评价。

Myocardial tissue engineering aims to repair, replace and regenerate damaged myocardium using cardiac tissue engineered in vitro. In this article, we reviewed the recent approaches in myocardial tissue engineering and their primary applications in vivo, and the cell sources, scaffold materials as well as the existing obstacles in this field were also discussed. Myocardial tissue engineering has an intriguing perspective for replace therapy, but it is in early stage. Its true value remains to be evaluated.