34例胎传梅毒临床分析

Clinical analysis of 34 congenital syphilis cases

目的探讨胎传梅毒的临床特征。方法回顾性分析浙江省遂昌县2001-2007年34例胎传梅毒患儿的临床表现、实验室检查和治疗转归情况。结果34例胎传梅毒患儿,无症状和体征的隐性胎传梅毒占17.65%。结论胎传梅毒患儿临床表现复杂,以早产、皮肤黏膜损害、肝脾肿大、呼吸道症状为多见,实验室及辅助检查以肝功能损害、胸片示肺感染、梅毒特征性骨损、蛋白尿和/或血尿、贫血和血小板减少为多见;无症状和体征的隐性胎传梅毒占一定比例;总体转归多良好。

Objective To discuss the clinical features of congenital syphilis. Methods The retrospective analysis was conducted on the clinical manifestations, laboratory examinations, treatment and outcomes of 34 congenital syphilis cases from 2001 to 2007 in Suichang. Results Asymptomatic congenital syphilis cases accounted for 17.65% of the total cases. Conclusion The clinical features of the children with congenital syphilis were complex, including premature birth, skin and mucous damage, splenohepatomegalia and respiratory symptoms. Liver function lesion, pulmonary infection, bone lesion, proteinuria/hematuria and anemia/thrombocytopenia were often found by laboratory tests and auxiliary examination. Asymptomatic congenital syphilis cases accounted for a certain proportion of the total cases; but most cases can be treated effectively.