新生儿下呼吸道感染的病原学分析

Aetiology analysis of lower respiratory tract infection in neonates

目的观察院内新生儿下呼吸道感染患者病原菌分布情况，为临床合理使用抗生素提供参考。方法对我院2006年2月-2008年9月医院新生儿下呼吸道感染的发生情况采用回顾性调查研究，并对医院感染病原菌分布进行统计分析。结果500份合格痰标本分离检出病原菌400株，检出率80．0％。其中革兰阴性杆菌250株，占62．5％；革兰阳性球菌80株，占20．0％；真菌70株，占17．5％。结论下呼吸道感染的病原菌以铜绿假单胞菌、肺炎克雷伯菌、不动杆菌都等最为常见。

Objective To observe the distribution of pathogens in lower respiratory tract infection in neonates for giving the suggestion in using antibiotics. Method 500 neonates with lower respiratory tract infection in our hospital from February 2006 to September 2008 were analyzed retrospectively and the distribution of pathogens were statistically analyzed. Results Among 500 sputum sample, 400 （80.0%） were identified pathogenic strains includ- ing 250 （62.5%） Gram-negative bacilli, 80 （20.0%） Gram-positive bacilli, and 70 07.5%） Fungi. Conclusion Gram-negative bacilli, Pseudomonas aeruginosa and Klebsiella pneumoniae were predominant pathogens of lower respiratory tract infection in neonates.