ACS患者血清sICAM-1、sVCAM-1、可溶性P选择素的水平变化及意义被引量：5

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摘要目的探讨血清可溶性细胞间黏附分子1(sICAM-1)、可溶性血管细胞间黏附分子1(sVCAM-1)、可溶性P选择素(sP选择素)在急性冠脉综合征(ACS)发生、发展中的作用。方法采用ELISA法测定50例ACS患者(ACS组)、40例稳定型心绞痛(SAP)患者(SAP组)及26例正常人(对照组)sICAM-1、sVCAM-1、sP选择素水平。结果ACS组血清sICAM-1、sVCAM-1、sP选择素水平显著高于SAP组和对照组(P均<0.01)。ACS组血清sI-CAM-1、sVCAM-1与sP选择素呈显著正相关(r=0.432、0.501,P均<0.05)。结论ACS患者血清sICAM-1、sV-CAM-1和sP选择素共同作用促进ACS的发生、发展。

作者李守贵

机构地区临沭县人民医院

出处《山东医药》 CAS 北大核心 2009年第17期84-85,共2页 Shandong Medical Journal

关键词细胞间黏附分子1 血管细胞黏附分子1 P选择素冠状动脉疾病

分类号 R541.4 [医药卫生—心血管疾病]

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