脑卒中患者血清总胆固醇与总胆汁酸水平测定

Determination of serum total cholesterol and total bile acid in patients with cerebral arterial thrombosis

目的:检测脑卒中患者血清总胆固醇(TC)与总胆汁酸(TBA)水平。方法:用酶法检测43例脑卒中患者(脑卒中组)、39例脑卒中合并高血压组(并发高血压组)及45例健康人(对照组)血清中TC及TBA水平。结果:脑卒中组血清TBA、TC分别为(5.09±1.51)μmol/L和(5.26±1.14)mmol/L,并发高血压组血清TBA、TC分别为(7.58±1.87)μmol/L和(7.24±1.39)mmol/L,均高于对照组[血清TBA、TC分别为(2.29±1.45)μmol/L和(4.26±1.08)mmol/L](P<0.05)。结论:脑卒中患者血清TBA水平升高,提示TBA在诊断脑卒中上有一定的价值。

Aim： To determine the levels of serum total bile acid（TBA） in patients with cerebral arterial thrombosis. Methods：The serum TBA and TC were determined using enzymatic test in 43 patients with cerebral arterial thrombosis （CAT group） , 39 patients with cerebral arterial thrombosis complicated with hypertension （CAT with hypertension group） and 45 normal persons （ control group）. Results： The serum levels of TBA and TC in CAT group were （5.09± 1.51 ） μmol/L, （5.26 ± 1.14） mmol/L,respectively, which were （7.58 ±1.87 ） μmol/L and （ 7.24 ±1.39 ） mmol/L in CAT with hypertension group respectively. They significantly higher than those in control group [ （2. 29 ±1. 45 ） μmol/L, （4.26 ±1.08） mmol/L] （P 〈 0.05 ）. Conclusion：Serum TBA level increases in patients with cerebral arterial thrombosis,wihich may be of some value in diagnosis of this disease.