MRI立体定向修正的研究及应用

Research and Application of MRI Correction in Stereotactic Radiotherapy

目的:探讨MRI图像用于立体定向放疗计划设计的可行性。方法:在实验研究MRI图像空间几何失真情况的基础上,重点探讨了MRI定位图像和定位标记畸变软件处理部分的实现。提出了由设计数据及采样数据生成原始稀疏修正数据,然后,以三线性插值生成与原始图像体素空间一致的修正数据来进一步修正患者图像的畸变修正算法;在算法研究的基础上,对MRIC系统进行了设计和实现。最后,用所研发的MRIC软件对试验获取的模体MRI畸变图像进行了处理。结果:MRIC系统纠正畸变MRI图像效果明显,所设计的修正算法有效。结论:通过图像处理软件对MRI进行修正,可以恢复图像的线性,使MRI定位图像直接用于立体定向放射治疗计划设计和定位成为可能。

Objective To discuss the feasibility of stereotactic radiotherapy plan designing based on MRI. Methods Based on the study of the serious geometric distortion of MRI while MRI was used in the condition of position by the experiment, how to deal with geometric distortion of MRI for patient positioning by the means of software was studied deeply. The basic thought of correction arithmetic for patient positioning images, of which the corrected data being used to correct patient images was created by primitive sparse corrected data calculated from design data and sampling data was brought forward. Supported by arithmetic research, the MRIC software system was designed and implemented. At last, the experiment model MRI was dealt with the MRIC system. Results The correction arithmetic was proved valid by the result of the experiment model MRI can be corrected back to normal state with MRIC system, which implemented the correction arithmetic. Conclusion It＇s possible that MRI would be used for positioning and plan designing in SRT.