期刊文献+

子宫颈癌切除术联合全盆腔照射的预后因素分析 被引量:3

原文传递
导出
摘要 目的探讨子宫颈癌切除术联合全盆腔照射的疗效及影响生存率的预后因素。方法回顾性分析77例根治性子宫颈癌切除术后联合全盆腔照射患者的临床资料,采用Kaplan-Meier法计算各亚组患者的生存率。各亚组生存率的比较应用Log-rank检验,预后的多因素分析采用Cox回归模型。结果随访时间为5~152个月,中位随访时间为33个月。全组患者1、3、5年的总生存率分别为89.5%、69.8%、51.9%。单因素分析显示患者年龄≤35岁、贫血、分期较晚、肿瘤直径≥4㎝、有淋巴结转移与预后差有关。多因素分析提示年龄、肿瘤直径、淋巴结是否转移是影响生存的独立预后因素。结论子宫颈癌切除术联合全盆腔照射患者的预后与多种因素有关,年龄是否≤35岁、肿瘤直径是否≥4cm、淋巴结是否转移是影响生存的独立预后因素。
出处 《苏州大学学报(医学版)》 CAS 北大核心 2009年第1期180-181,共2页 Suzhou University Journal of Medical Science
  • 相关文献

参考文献8

  • 1Davies P, Aryn M, Dillner J, et al. A report on the current status of European research on the use of human papillomavirus testing for primary cervical cancer screening[J]. Int J Cancer, 2006, 118 (4): 791-796.
  • 2Rutledge FN, Mithell MF. Youth as a prognostic factor in carcinoma of the cervix a matched analysis [J].Gynecol Oncol, 1992 (2), 44: 123-127.
  • 3谢虹.66例宫颈癌的临床特点分析[J].苏州大学学报(医学版),2006,26(5):901-902. 被引量:1
  • 4罗仪,赵昌银,王剑.年轻宫颈癌患者预后不良的分子病理因素分析[J].中国综合临床,2007,23(5):468-470. 被引量:3
  • 5程玺,蔡树模,李子庭,王香娥,丁亚琴,薛木泉.宫颈癌淋巴结阴性患者的预后及其危险因素[J].中国癌症杂志,2003,13(6):534-536. 被引量:6
  • 6~ Nakanishi T, Ishikawa H, Nawa A, et al. The Significance of Tumor Size in CIinical Stage I b Cerbical Cancer:. Can a Cut-off Figure be Determined[J]. Int J Gynecol Cancer, 2000, 10(5): 397.
  • 7Eralp Y, Saaip P, Sakan B, et al. Prognostic Factors and Survival in Patients with Metastatic or Tecurrent Carcinoman of the Uterine Cervix[J]. Int J Gynecol Cancer, 2003, 13(4): 479-504.
  • 8Kobierski J, Emerich J, Krolikowska B, et ol. Lymph node metastasis as a prognostic factor in cervical carcinoma[J]. Ginekol Pol, 2002, 73( 11 ): 925-929.

二级参考文献27

  • 1姜继勇,陈雪莲.青年人宫颈癌临床病理特征和预后的研究[J].临床肿瘤学杂志,2005,10(1):45-48. 被引量:6
  • 2郎景和.子宫颈癌及其普查[J].现代妇产科进展,1994,3(3):275-278. 被引量:73
  • 3赵恩锋,鲍嫘,李超,宋磊,李亚里.近50年宫颈癌的发病趋势和临床特点分析[J].解放军医学杂志,2005,30(7):644-646. 被引量:47
  • 4[1]Monk B J, Cha DS, Walker JL, et al. Extent of disease as an indication for pelvic radiation following radical hysterectomy and bilateral pelvic lymph node dissection in the treatment of stage IB and ⅡA cervical carcinoma[ J]. Gynecol Oncol, 1994,54 (1) :4-9.
  • 5[2]Green JA, Kirwan JM, Tierney JF, et al. Survival and recurrence after concomitant chemotherapy and radiotherapy for cancer of the uterine cervix: a systematic review and Metaanalysis[ J]. Lancet,2001,358(9284) :781-786.
  • 6[3]Morris M, Eifel PJ, Lu J, et al. Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer[ J]. N Engl J Med, 1999,340 ( 15 ):1137-1143.
  • 7[4]Keys HM, Bundy BN, Stehman FB, et al. Cisplatin, radiation,and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma [ J]N Engl J Med,1999, 340(15): 1154-1161.
  • 8[5]Peters WA 3rd, Liu PY, Barrett RJ 2nd, et al. Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix [ J]. J Clin Oncol,2000,18(8): 1606-1613.
  • 9[6]Whitney CW, Sause W, Bundy BN, et al. Randomized comparison of uorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stages ⅡB-ⅣA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group study [ J ]. J Clin 0ncol,1999,17(5): 1339-1348.
  • 10[7]Rose PG, Bundy BN, Watkins EB, et al. Concurrent cisplatinbased radiotherapy and chemotherapy for locally advanced cervical cancer[J]. N Engl J Med, 1999,340( 15): 1144-1153.

共引文献7

同被引文献25

引证文献3

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部