乌龙药茶对高脂血症大鼠血脂代谢、尿酸代谢的影响

Effects of Oolong Herb Tea on Blood Lipids and Uric Acid Metabolism in Experimental Hyperlipidemia Rat

观察乌龙药茶对高脂血症大鼠血脂水平、尿酸水平调节,以及对肝组织的影响。采用高脂并酒精喂养大鼠建立高脂血症模型,通过药、茶和乌龙药茶分别灌胃,观察大鼠的一般情况及肝、肾组织的病理变化,检测大鼠丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、总胆固醇(TCHO)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、尿酸(UA)、黄嘌呤氧化酶(XOD)的含量。结果为药、茶和乌龙药茶均能显著降低模型大鼠血液ALT、AST、UA、TCHO、TC、LDL-C、UA、XOD含量,提高HDL-C含量(P<0.05,P<0.01),其中,乌龙药茶作用显著优于药、茶。研究结论,药、茶和乌龙药茶均能显著调节机体的血脂水平和尿酸水平,乌龙药茶表现为药与茶两者协同作用,提示乌龙药茶对高脂血症具有一定的预防保健作用。

The effects of oolong herb tea on the serum lipid level and uric level and the influence of liver tissue in Expermental Hyperlipidemia Rats were investigated. To establish the hyperlipidmia rat model by feeding of high lipid diet and ethanol, as well as feed the herb, tea and oolong herb tea by intragastic for 35 days, measure the level of ALT, AST, TCHO, TG, HDL-C, LDL-C, as well as the contents of UA and XOD in rat blood. The general conditions and histopathological changes in tissues of liver and kidney were observed. Results showed that the herb, tea and oolong herb tea could reduce significantly the TCHO, TC, LDL-C, TCHO, UA and XOD and increase the HDL-C level （P〈0.05, P〈0.01）. The effect of oolong herb tea was more remarkable than that of herb and tea treatment. It is concluded that the herb, tea and oolong herb tea are able to regulate the level of serum lipid and uric acid effectively, and showed a protective effect of vein endothelium cells. It is showed that the synergistic effect between herb and tea and improve the efficacy in oolong herb tea.