摘要
目的探讨奥扎格雷钠对急性脑梗死(ACI)患者血清白介素-6(IL-6)和可溶性细胞间黏附分子-1(sICAM-1)的影响。方法80例ACI患者随机分为治疗组和对照组。2组均给予常规治疗,治疗组加用奥扎格雷钠治疗,对照组加用维脑路通,采用双抗体酶联免疫吸附法(ELISA)分析。结果2组治疗后血清IL-6和sICAM-1水平均降低,治疗组下降更明显。结论血清sICAM-1及IL-6水平升高可能是脑梗死发病的危险因素,奥扎格雷钠对急性脑梗死患者血清中异常升高的IL-6和sICAM-1有降低作用。
Objective To study the influence of Ozagrel on serum interleukin-6 （IL-6） and intercellular adhesion molecule-1（sICAM-1） in patients with acute cerebral infarction. Methods Eighty patients were randomly divided into two groups： controlled group （40 cases） and compared group （40 cases）. In addition to regular treatment, controlled group was given Ozagrel, compared group was given Weinaolutong. Double anti-body enzyme-linked immuno-sorbent assay was used. Results After treatment,serum IL-6 and sICAM-1 decreased in both groups, but the controlled group decreased significantly. Conclusion The level of serum IL-6 and sICAM-1 probably are the risk factors of cerebral infarction. Ozagrel has an obvious effect on abnormally elevated serum IL-6 and sICAM-1 in patients with acute cerebral infarction.
出处
《中国实用神经疾病杂志》
2009年第8期20-22,共3页
Chinese Journal of Practical Nervous Diseases
