阻塞性睡眠呼吸暂停低通气综合征患者主观评估与客观检查的相关性研究

Correlation between subjective assessment and objective measurement in obstructive sleep apnea hypopnea syndrome

目的探讨阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)患者主观评估和客观检查的相关性。方法分别采用视觉模拟量表(visual analogue scale,VAS)、Epworth嗜睡量表(Epworth sleepiness scale,ESS)和Calgary睡眠呼吸暂停生活质量指数量表(sleep apnea quality of life index,SAQLI)评估200例OSAHS患者的打鼾、嗜睡症状和生活质量,分析它们与多导睡眠仪(polysomnography,PSG)检查间的相关性。结果VAS、ESS与PSG间有一定的相关性,但不同呼吸暂停低通气指数(apnea hypopnea index,AHI)和最低血氧饱和度(lowest oxygen saturation,LSaO2)组间只有重度组VAS和ESS值与其他各组间差异有统计学意义。SAQLI同PSG间没有良好的相关性,而且不同AHI和LSaO2组间只有重度低血氧组的症状维度分值与其他各组间差异有统计学意义。结论评估OSAHS患者须结合主观评估和客观检查。VAS和ESS在评估病情严重程度上的价值不大。

Objective To investigate the correlation between subjective assessment and objective measurement in obstructive sleep apnea hypopnea syndrome （OSAHS）. Methods Data of 200 OSAHS patients were analyzed retrospectively. Assessment of snoring was achieved by visual analogue scale （VAS）. Assessment of excessive daytime sleepi- ness was achieved by Epworth sleepiness scale（ESS）. The quality of life was assessed by sleep apnea quality of life index （SAQLI）. The correlation between the scores and polysomnography（PSG） parameters was statistically analyzed. Results VAS and ESS had significant correlation with PSG parameters respectively. However, only the mean ESS and VAS in severe OSAHS group or in severe hypoxemia group was higher than that in other groups. There was no good correlation between SAQLI and PSG parameters. And only the mean of symptom domain in severe hypoxemia group was significantly lower than that in other groups. Conclusions Both subjective assessment and objective examination must be considered to evaluate OSAHS patients. Either ESS or VAS had little value in the assessment of OSAHS.