脑梗死患者病灶部位与认知损伤的相关性研究

Correlation of Lesion Sites and Cognitive Injury in Cerebral Infarction Patients

目的:研究无痴呆脑梗死患者病灶部位与认知损伤特点的相关性。方法:选择无痴呆的脑梗死患者89例为梗死组,55例健康老年人为对照组,均进行基本认知功能测定,分析比较。结果:梗死组平均认知总分低于对照组(P<0.05);多发性脑梗死患者的智能损伤特点依序为数字工作记忆>知觉速度>记忆>思维效率>空间能力;基底核梗死患者智能损伤排序为数字工作记忆>知觉速度>旋转量>记忆量>心算速率。结论:无痴呆的脑梗死患者认知能力已有明显损伤,尤其是多发性脑梗死和基底核梗死患者的工作记忆、知觉速度受损更为明显。

Objective： To investigate the relation of lesion sites and cognitive function impairment in cerebral infarction patients without dementia. Methods： Eighty-nine cerebral infarction patients without dementia （observation group） and 55 healthy elderlies （control group） were recruited for this study. Results： The average score of cognitive function in the observation group was lower than those in the control group （P〈0.05）. Especially, significant differences in cognitive impairment were observed between patients with multiple cerebral infarction and those with basal ganglia infarction. The levels of cognitive impairment in multiple cerebral infarction patients were presented in follow order., digital working memory, perceptual speed, memory, thinking efficiency, and space capabilities. For cases with basal ganglia infarction, the levels of cognitive impairment followed this order： digital working memory, perception speed, rotation＇ s capacity, memory＇ s capacity, and mental arithmetic speed. Conclusion： The impairment in cognitive function is impressive in cerebral infarction patients without dementia. The perception speed and digital working memory are more likely to be damaged in patient with multiple cerebral infarction and basal ganglia infarction .