儿童长骨非骨化性纤维瘤

Non-ossifying Fibroma of Long Bone in Children

目的：探讨儿童长骨非骨化性纤维瘤的临床特点、诊治方法及预后。方法：总结１９８８～１９９７年收治发生在长骨的非骨化性纤维瘤６例。其中男２例，女４例，平均年龄１０．１岁。单发病灶在胫骨４例；多发性２例，同时发生在胫、腓骨１例，胫骨、腓骨及双侧股骨同时４处受累１例。６例均行手术治疗，包括单纯刮除加植骨和瘤段切除加游离腓骨移植。结果：６例均病理证实为非骨化性纤维瘤。随诊最长８年７个月，无一例复发。结论：该瘤病因尚不明确，可能为生发在骨内纤维组织的良性肿瘤。临床上应与纤维性皮质骨缺陷、骨纤维结构不良、骨巨细胞瘤、单发性骨囊肿等相鉴别。对较大病灶，在瘤灶刮除后采用带血管腓骨移植或带血管蒂腓骨移位植骨的治疗方法，具有骨愈合过程快、患骨可及早负重的优点。

Objective: To study the characteristics, diagnosis, treatment and prognosis of non-ossifying fibroma of the long bone in children. Methods: Six children (male 2, female 4, mean age 10.1 years) with nonossifying fibroma of long bone were admitted from 1988 to 1997. Of them, the solitary lesion in 4 cases were located in tibia, and the rest were multiple lesions. All cases underwent operation including curettage of foci and iliac autotransplantation, or segmental resection and free vascularized fibula transplantation. The diagnosis was confirmed histologically. The followup was 8 years and 7 months without recurrence. Conclusions: The cause of nonossifying fibroma is uncertain, it may be a benign tumor originated from the osseofibrous. It should be differentiated from osteofibrous dysplasia, giant cell tumor, single bony cyst etc. The advantage of curettage of foci and autogenous bone grafting are rapid bony healing and early weight carrying.