女性间质性膀胱炎和膀胱过度活动症的尿动力学比较研究

Urodynamic studies of interstitial cystitis and overactive bladder in women

目的对比研究女性间质性膀胱炎(interstitial cystitis,IC)和膀胱过度活动(overactive bladder,OAB)患者的尿动力学特征。方法回顾性研究21例IC患者和32例OAB患者(均为女性)的尿动力学表现差异。结果IC组最大尿流率(Qmax)、初始尿意容量(VFD)、最大尿意容量(MV)以及膀胱顺应性(BC)均明显小于OAB组(P<0.05),OAB组发生逼尿肌过度活跃(detrusor overactivity,DO)25例(78.1%),IC组2例(9.5%),2组DO例数上亦有明显差异(P<0.05)。结论女性IC患者和OAB患者在临床上表现有较大相似性,但两者的尿动力学表现在很多方面均存在差异。尿动力学检查是鉴别IC和OAB的重要方法。

Objective To investigate the urodynamic characteristics of female patients with interstitial cystitis （IC） or overactive bladder （OAB）. Methods The NIDDK criteria have been used for clinical diagnosis. 21 female patients with IC and 32 female patients with OAB underwent a standard urodynamic examination. The 2 groups were compared and statistically analyzed. Results There were significant differences between the IC group and the OAB group in following parameters（P 〈 0. 05 ） ： Qmax maximal volume at micturition desire（MV） ,volume at first desire （VFD） and bladder compliance （BC）. Moreover 2 out of 21 patients of IC group （9.5%） vs 25 out of 32 patients of OAB group （78.1%） had detrusor overactivity （DO） （P 〈0.05）. Conclusion OAB can be distinguished from IC by several differences. Therefore, urodynamic examination is a valuable diagnostic tool for differential diagnosis of IC and OAB.