青少年特发性脊柱侧凸伴发骨密度减低

Adolescent Idiopathic Scoliosis Associated with Low Bone Mineral Density

双能量Ｘ线吸收测量仪（ＤＥＸＡ）是目前临床测量骨矿物质密度（ＢＭＤ）及诊断骨质疏松症普遍应用的方法。本研究旨在用ＤＥＸＡ测量特发性脊柱侧凸患者的ＢＭＤ，总体比较特发性脊柱侧凸患者与同龄正常人ＢＭＤ的差别以及调查特发性脊柱侧凸患者ＢＭＤ异常的发生率。用ＤＥＸＡ测量了８１例１２～１４岁特发性脊柱侧凸患者及２２０名同年龄健康对照的腰椎及双侧近端股骨ＢＭＤ。结果显示，所有三个年龄组脊柱侧凸组ＢＭＤ值均低于正常对照组。４５％特发性脊柱侧凸患者ＢＭＤ水平在正常范围，５５％伴骨质稀少或骨质疏松。

ual-energy X-ray absorptiometry (DEXA) is a standard methodology in bone density measurement and clinical diagnosis of osteoporosis. Aims of the present study were to evaluate the bone mineral status using DEXA, to investigate whether the bone mineral density (BMD) in patients with adolescent idiopathic scoliosis differs from healthy individuals, and incidence of abnormal bone mineral status in patients with adolescent idiopathic scoliosis. BMD was measured using DEXA in the lumbar spine and bilateral proximal femur on 81 girls with adolescent idiopathic scoliosis and 220 age matched healthy controls. Results indicated 45% of scoliotic subjects with BMD in normal range, and 55% of them suffering from osteopenia or even osteoporosis.