33例儿童功能性消化不良的胃动力改变

Changes of gastric motility in 33 pediatric patients with functional dyspepsia

探讨小儿功能性消化不良的胃动力学改变。材料和方法：采用超声显象仪、胃肠电分析仪、血浆胃动素，测定了33例功能性消化不良小儿的胃动力学。结果：26例半排空时间显著延长，25例胃电节律异常。用普瑞博恩治疗后胃窦收缩频率由1．94±0．94增加到3．68±0．68次／分，收缩幅度由37．97±8．96增加到58．56±10．75mm，胃半排空时间由49．36±11．53缩短到26．36±8．01min。胃电节律紊乱均趋正常，参数离散好转。结论：胃运动功能障碍是小儿功能性消化不良主要发病机制之一。

Objective:To ascertain the rule of gastric motility in functional dyspepsia (FD)among children. methods:we studied 33 cases of FD with age range of 4～12 years old,gastric emptying function and serum motilin were measuredby ultrasonography,eletrogastrography(EGG )and RIA. Results: The results showed gastric half emptying time (T1/2)of26 cases was delayed, EGG in 25 was abnormal. Furthermore, we also observed the prepulsid effect on gastric motility. Dimensions and frequencies of gastric contractions before and after prepulsid were 37. 97±8. 96mm, 1. 94±0. 94time/min and 58. 56±10. 75mm, 3. 68±0. 68time/min respectively. T1/2 was shortened form 49. 36±11. 53min to 26. 36±8. 01min. There was no EGG abormality found. Conclusion:Gastric motility dysfunction might be one of the main causesof FD in children.