期刊文献+

Drug-induced liver injury due to “natural products” used for weight loss:A case report 被引量:2

Drug-induced liver injury due to "natural products" used for weight loss:A case report
下载PDF
导出
摘要 Taking herbal-extracts to lose weight is an underestimated health hazard.Often,these products contain active agents that can cause acute liver damage.In this case report,a 22-year-old female patient,who presented with a feature of cholestatic syndrome,was so sure that the "natural products" were not dangerous that she did not inform her physicians that she had taken them,making their task that much more challenging.Clinical presentation mimicked acute cholecystitis and the patient underwent a cholecystectomy.Surgery was without any consequences and complications,although it did not completely cure the illness.She later admitted to having taken herbal remedies and this led to the correct diagnosis of phytotherapy-related hepatotoxicity and a successful therapeutic approach.The true incidence of phytotherapy-related hepatotoxicity and its pathogenic mechanisms are largely unknown.It is important to increase the awareness of both clinicians and patients about the potential dangers of herbal remedies. Taking herbal-extracts to lose weight is an underestimated health hazard. Often, these products contain active agents that can cause acute liver damage. In this case report, a 22-year-old female patient, who presented with a feature of cholestatic syndrome, was so sure that the "natural products"were not dangerous that she did not inform her physicians that she had taken them, making their task that much more challenging. Clinical presentation mimicked acute cholecystitis and the patient underwent a cholecystectomy. Surgery was without any consequences and complications, although it did not completely cure the illness. She later admitted to having taken herbal remedies and this led to the correct diagnosis of phytotherapy-related hepatotoxicity and a successful therapeutic approach. The true incidence of phytotherapy-related hepatotoxicity and its pathogenic mechanisms are largely unknown. It is important to increase the awareness of both clinicians and patients about the potential dangers of herbal remedies.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第19期2414-2417,共4页 世界胃肠病学杂志(英文版)
关键词 Drug-induced liver injury OBESITY Herbalremedies CHOLECYSTITIS 药物性肝损害 天然产品 病例报告 减肥 中草药提取物 胆汁淤积综合征 植物疗法 急性肝损伤
  • 相关文献

参考文献15

  • 1Danan G,Benichou C.Causality assessment of adverse reactions to drugs--I.A novel method based on the conclusions of international consensus meetings:application to drug-induced liver injuries.J Clin Epidemiol 1993; 46:1323-1330
  • 2Conti E,De Checchi G,Mencarelli R,Pinato S,Rovere P.Lycopodium similiaplex-induced acute hepatitis:a case report.Eur J Gastroenterol Hepatol 2008; 20:469-471
  • 3Stickel F,P?schl G,Seitz HK,Waldherr R,Hahn EG,Schuppan D.Acute hepatitis induced by Greater Celandine (Chelidonium majus).Scand J Gastroenterol 2003; 38:565-568
  • 4Crijns AP,de Smet PA,van den Heuvel M,Schot BW,Haagsma EB.[Acute hepatitis after use of a herbal preparation with greater celandine (Chelidonium majus)] Ned Tijdschr Geneeskd 2002; 146:124-128
  • 5Kosina P,Walterová D,Ulrichová J,Lichnovsky V,Stiborová M,Rydlová H,Vicar J,Krecman V,Brabec MJ,Simánek V.Sanguinarine and chelerythrine:assessment of safety on pigs in ninety days feeding experiment.Food Chem Toxicol 2004; 42:85-91
  • 6Takayama H,Katakawa K,Kitajima M,Yamaguchi K,Aimi N.Ten new Lycopodium alkaloids having the lycopodane skeleton isolated from Lycopodium serratum Thunb.Chem Pharm Bull (Tokyo) 2003; 51:1163-1169
  • 7Woolf GM,Petrovic LM,Rojter SE,Wainwright S,Villamil FG,Katkov WN,Michieletti P,Wanless IR,Stermitz FR,Beck JJ,Vierling JM.Acute hepatitis associated with the Chinese herbal product jin bu huan.Ann Intern Med 1994;121:729-735
  • 8Choy CS,Cheah KP,Chiou HY,Li JS,Liu YH,Yong SF,Chiu WT,Liao JW,Hu CM.Induction of hepatotoxicity by sanguinarine is associated with oxidation of protein thiols and disturbance of mitochondrial respiration.J Appl Toxicol 2008; 28:945-956
  • 9Stickel F,Egerer G,Seitz HK.Hepatotoxicity of botanicals.Public Health Nutr 2000; 3:113-124
  • 10Gordon DW,Rosenthal G,Hart J,Sirota R,Baker AL.Chaparral ingestion.The broadening spectrum of liver injury caused by herbal medications.JAMA 1995; 273:489-490

同被引文献1

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部