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卵巢切除影响椎体力学强度的实验研究

Experimental Research of Ovariectomy Effect on Mechanical Strength in Rat Vertebrae
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摘要 选用３个月龄ＳＤ雌性大鼠６４只，分卵巢切除（ＯＶＸ组）和假手术（Ｓｈａｍ－Ｏ组）；术后第１，３，５，７月取Ｌ２椎体．在测量椎体几何形态后，进行垂直压缩试验，持续记录负载变形曲线．结果显示：ＯＶＸ组椎体平均高度减低（Ｐ＜００５），椎体上端前后缘变大（Ｐ＜００５），说明骨质疏松时椎体可能发生了楔形改变，椎体上端矢状径的改变较明显．ＯＶＸ组１月时椎体载荷及能承受的应力等均已明显下降（Ｐ＜００１），７月时降至低值．椎体力学强度的减低。 Chosen were 64 SD female rats aged 3 months, which were divided into two groups: ovariectomy (OVX group) and sham operation (Sham-O group). L vertebrae were postoperatively taken in the 1st, 3rd, 5th and 7th month. Morphogeometric measurement
作者 胡侦明 戴克戎 薛文东 汤亭亭 张先龙
机构地区 昆明医学院第二附属医院骨科 上海第二医科大学附属第九人民医院骨科
出处 《昆明医学院学报》 1998年第2期50-52,共3页 Journal of Kunming Medical College
关键词 卵巢切除 椎体 力学强度 骨质疏松 大鼠 Ovariectomy,Vertebrae,Mechanical strength,Rat
分类号 R681.02 [医药卫生—骨科学] R588 [医药卫生—内分泌]
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参考文献10

  • 1Lin B Y,Jee W S S.Chen M,et al Mechanical loading modifies ovariectomy - inducett cancellcus bone loss Bone Miner, 1994,25 : 199.
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二级参考文献8

  • 1B. D. Snyder,S. Piazza,W. T. Edwards,W. C. Hayes. Role of trabecular morphology in the etiology of age-related vertebral fractures[J] 1993,Calcified Tissue International(1):S14～S22
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  • 7Dr. Catherine Bergot,Anne-Marie Laval-Jeantet,Fran?oise Prêteux,Alain Meunier. Measurement of anisotropic vertebral trabecular bone loss during aging by quantitative image analysis[J] 1988,Calcified Tissue International(3):143～149
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共引文献8

昆明医学院学报
1998年 第2期

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